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Qualia Mind Works (My 2024 Review)
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Qualia Mind Works (My 2024 Review)

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Qualia Mind has extensive fitness and wellness influencers backing it. So it must be good, right?

I tried it to see for myself if Qualia Mind has what it takes to be a premium cognitive enhancer, as they claim. It turns out these influencers may be right.

Pros

  • Stimulant & Stimulant Free: You have an option to purchase with or without caffeine for those who are sensitive or want to take it in the late evening.
  • Enhances Cognitive Function: Increases focus, mental energy, and information processing speed.
  • Designed For Short & Long-Term Brain Health: Most people are searching for an instant brain boost, which Qualia Mind provides. But the formulation also promotes long-term brain health.

Cons

  • Price: This is the most expensive nootropic supplement at $159 a bottle and $6-7 per serving.
  • Dosage Requirements: Taking seven capsules daily can be cumbersome for some users.

Who Are Neurohacker Collective (Qualia Mind)

Neurohacker Collective is a company founded to optimize individual and collective wellbeing by applying complex systems science.

They focus on creating supplements that support cognitive function, mental health, and overall physical wellness.

Their approach combines rigorous scientific research with holistic health principles, aiming to address the root causes of health issues rather than just symptoms.

The team includes experts from diverse backgrounds, including medicine, research, and integrative health, ensuring their products are innovative and grounded in proven methodologies.

Qualia Mind

Qualia Mind Nootropic

A premium nootropic blend designed for short and long term brain boosting benefits.

CHECK CURRENT DEALS
Qualia Mind

Qualia Mind Ingredients

Qualia Mind Ingredients

Acetyl L-Carnitine 500 mg

Although more research is needed, L-carnitine has not been shown to improve cognitive function as a supplement in healthy adults [40].

However, it shows promise in adults with cognitive deterioration but yields variable results. It is thought to work by improving cell membrane health, increasing cellular energy generation, defending against toxins, and stimulating growth factors essential for brain cell survival [41].

Notably, reduced levels of acetyl L-carnitine in people with Alzheimer’s and memory problems point to its potential for early detection and treatment.

Animal studies support its neuroprotective and cognitive benefits, implying that ALC could reverse aging and increase brain function [42].

Human studies, on the other hand, have produced a variety of results, including alterations in brain chemistry and function in Alzheimer’s patients, as well as improvements in cognitive impairments in other populations [43].

Furthermore, it may aid in weight loss in some circumstances and decrease depression symptoms [44][45].

Artichoke Leaf Extract 400 mg

Qualia Mind Benefits

Artichoke extract is renowned for its prebiotic qualities, which increase the growth of probiotic bacteria in the stomach, potentially improving cognitive performance in rats [1].

Combining artichoke extract with aerobic training enhanced cognitive status in elderly people with mild cognitive impairment while also lowering blood glucose and insulin resistance [2].

Artichoke variations Spinoso Sardo and Romanesco Siciliano showed antioxidant capabilities and possible preventive effects against cardiovascular and neurological illnesses, with Romanesco Siciliano having more antioxidant power [3].

The 400 mg dose is significantly lower than the doses utilized in these studies.

Bacopa Monnieri 300 mg

Bacopa monnieri is a traditional plant that has been shown to boost cognitive function, particularly memory.

Studies have shown that bacopa extract, namely bacosides A and B, improves memory formation, recall, and cognitive function [4].

It has neuroprotective characteristics and is used to treat cognitive problems like Alzheimer’s disease.

Adults should take 200 to 400 mg daily. Bacopa is generally well tolerated, with only a few complaints of mild sleepiness or stomach problems.

Clinical trials suggest older people have superior memory, attention, mood, and cognitive abilities [5][6][7]. However, more research is needed to comprehend fully how useful it is across multiple cognitive areas.

Qualia Mind contains 300 mg of Bacopa, which is the recommended dose to experience these effects.

Rhodiola Rosea 300 mg

Is Qualia Mind Healthy

Rhodiola Rosea is a plant used in herbal medicine for its adaptogenic characteristics, which assist the body in managing stress. It contains active substances such as salidroside and rosavin, which protect brain cells.

Rhodiola Rosea has been shown in studies to boost mood and lessen symptoms of anxiety, stress, and depression [8].

It may also provide some cognitive benefits, but the evidence is limited. The suggested daily dosage is 100-170 mg, with a rosavin content of 3.6-6.14 mg [9].

Qualia Mind includes 300 mg of Rhodiola Rosea extract, within the recommended range of 4.5 mg.

While typically safe, it is not recommended for people suffering from disorders such as manic-depressive psychosis. Youngsters, pregnant or nursing women, and people with high blood pressure should avoid it.

Phenylalanine 300 mg

L-phenylalanine is an essential amino acid that has been studied for its possible benefits in treating illnesses such as attention deficit disorder and depression.

In studies, dosages of up to 1200 mg improved mood and focus in people with attention deficit disorder, but tolerance developed after 2-4 months [10].

In another study of people with depression, a dosage range of 75-200 mg/day for 20 days resulted in significant improvements in 12 of the 20 patients [11].

However, the efficiency and safety of L-phenylalanine varies, and it is used to treat a variety of illnesses, including depression and arthritis, as well as aiding in addiction rehabilitation [12].

L-Tyrosine 250 mg

Research has demonstrated the amino acid L-tyrosine can raise brain dopamine levels. Cognitive control, especially in mentally demanding scenarios, has been enhanced by L-tyrosine supplementation [13].

Dopamine influences cognitive flexibility, which is where it shines.

In stressful or mentally challenging conditions, L-Tyrosine can be helpful, but it doesn’t hold much promise for addressing clinical disorders or enhancing physical activity.

It provides the most significant cognitive benefits when neurotransmitter activity is regular, but dopamine and norepinephrine levels are temporarily reduced [14].

According to studies, the best dose for cognitive improvement begins at 2 grams. That is a lot more than the dosage included in Qualia Mind.

Taurine 200 mg

Taurine and caffeine work together brilliantly. Higher amounts of taurine are associated with improved performance, and consuming more reduces the requirement for caffeine to have the same effect [15].

It is dosage-independent and enhances endurance performance with a 1–6 g dose before exercise [16].

L-Theanine 200 mg

L-Theanine has a reputation for improving mental health, with research showing that daily doses of 200-400 mg lower stress and anxiety [17][18].

The caffeine L-theanine stack enhances both physical and cognitive performance.

Some advantages include faster reaction time, faster visual processing, improved working memory, increased awareness, and less tiredness and mental fatigue [19][20].

The experiments employ a 2:1 L-theanine to caffeine ratio. Qualia Mind utilizes the same ratio, which means it’s effective.

Alpha-GPC 200 mg

The choline-containing phospholipid alpha GPC enhances cognitive performance in neurological disorders such as dementia [21].

According to research, it improves memory and focus, possibly benefiting brain health.

Clinical trials have shown it can improve cognitive performance, particularly in conjunction with other therapies such as donepezil [22].

It is generally safe and well-tolerated. The amino acid alpha GPC raises acetylcholine levels in the brain, which are necessary for memory and learning [23].

It is used as both a medication and a dietary supplement. Alpha GPC improves cognitive performance, especially in cases of adult-onset dementia [24].

However, 200 mg of Alpha GPC may boost vertical jump performance similarly to coffee [25].

Citicoline 150 mg

Citicoline is commonly mentioned in discussions about memory enhancement. According to studies, 500 mg per day may improve episodic memory or the ability to recall personal experiences and specific events, especially in the elderly [46].

Other studies suggest that taking at least 500 mg of this supplement daily may provide cognitive benefits to healthy adults [47].

150 mg of citicoline is present in Qualia  Mind, far less than the 500 mg dosage used in the research.

Organic Coffeeberry (90 mg caffeine)

Caffeine is a potent stimulant that increases power and sprint performance by 6.5% while increasing the number of reps accomplished when lifting by 9.4% [26].

It also increases endurance performance by 2.22% in time trials and 2.9% in power output when compared to a placebo [27].

Caffeine doses range from 3 to 6 mg per kilogram of body weight, improving performance with each dosage in this range.

Qualia Mind contains 90 mg of caffeine, which is a relatively low quantity and does not meet the performance-enhancing range, but it can still provide effect for some people. [28][29]

Velvet Bean – L-Dopa 100 mg

Can You Take Qualia Mind Every Day

Velvet beans may possess neuroprotective properties [30]. However, no evidence exists that the chemical ingredient L-dopa improves learning and cognitive performance in healthy individuals [31].

This involved ingesting 100 mg of L-dopa and 25 mg of benserazide. Qualia Mind includes 100 milligrams of L-dopa.

Phosphatidylserine 100 mg

Phosphatidylserine is vital for proper brain function. Phosphatidylserine is essential for maintaining nerve cell membranes and myelin, which are required for successful neurotransmission [32].

Phosphatidylserine can help to counteract cognitive loss as the brain ages by boosting memory formation, learning, focus, and problem-solving [33].

It is easily absorbed in humans and penetrates the blood-brain barrier.

Phosphatidylserine supplements have been shown to increase cognitive function and are generally well tolerated, with suggested daily doses ranging from 100 to 800 mg [34][35].

Qualia Mind contains 100 mg of phosphatidylserine, which may provide these cognitive-enhancing effects.

Algae DHA 80 mg

DHA is an essential component of neuronal membranes that promotes brain health and cognitive function.

Adult mental abilities are enhanced by DHA ingestion, particularly when combined with eicosapentaenoic acid (EPA) [36].

This effect is most evident in elderly adults with mild memory issues. Higher DHA and EPA concentrations (over 1 g per day) have been linked to improved episodic memory.

Observational studies have also found a connection between DHA/EPA intake and memory performance in the elderly. DHA, alone or in conjunction with EPA, improves memory in the elderly.

Ginko Biloba 50 mg

Ginkgo biloba extract is used to improve cognitive performance. Its constituents contain antioxidants, which improve blood flow and have anti-inflammatory qualities.

Ginkgo biloba extract has been found to alleviate chronic brain problems in animal experiments by altering inflammatory mediators and the cholinergic system [37].

It has been demonstrated in clinical trials to improve working memory and processing speed [38]. However, its efficacy in healthy adults under the age of 60 remains uncertain [39].

Typical daily doses range from 120 to 300 mg. Although side effects are rare, they can include stomach irritation and headaches, which may cause blood to thin in individuals taking certain drugs.

Qualia Mind contains 50 mg of Ginkgo Biloba, which falls below the recommended dose range.

Coleus Forskohlii 20 mg

I’m not aware, nor could I find any data relating coleus forskohlii to cognitive enhancement. This Indian medicinal herb is known for its fat-burning qualities.

According to one review, Coleus forskohlii extract considerably affected weight loss [48].

However, this review contains two main errors. To begin, the review was undertaken by a research advisor for the DHC Corporation laboratory.

A short Google search reveals that they sell several supplements. I don’t blame them; most supplements can’t be studied due to insufficient funds. However, the primary issue is their data.

The review included open trial studies without blinding, which boosted placebo outcomes. Furthermore, the randomized control trials selected were funded by supplement distributors [49].

Or demonstrated no fat-loss advantages [50].

Huperzine A 5 mg

Huperzine-A stands out as a promising speculative substance because of its potential to improve cognitive function and help Alzheimer’s patients [40].

Contact, collision, and combat athletes may benefit from taking 1mg/kg of bodyweight daily to treat traumatic brain damage [41].

However, the immediate cognitive or physical benefits of Huperzine-A have yet to be decisively established. Therefore, its position remains uncertain until more research [42].

Qualia Mind includes only 5 mg of Huperzine-A, which is drastically lower than the recommended 1 mg/kg body weight.

Qualia Mind Price

I couldn’t believe my eyes with how much Qualia Mind costs. I broke it down for you below.

Qualia MindPricePrice per Serving
1 Bottle (22 servings)$159$7.22 per serving for one-time purchase
1 Bottle (22 servings)$139$6.31 per serving with subscription. The first bottle costs $39

This is the most expensive nootropic available, being almost four times the price per serving than similar formulations like NooCube and Mind Lab Pro.

However, Qualia Mind stands behind their product, offering a no hassle, no return 100% money-back guarantee. They’ll refund you if you don’t like it for whatever reason.

Qualia Mind Benefits

Qualia Mind Cognitive Supplement

Enhance Focus And Alertness

When a nootropic is formulated correctly, you will experience enhanced focus, alertness, and energy, but without the big jumps and crashes other stimulants provide. So you are getting only the benefits without the drawbacks.

Some of the 28 ingredients have been proven to bring benefits, while others are more speculative. The formula of Qualia Mind also benefits from the synergizing effects of some ingredients, improving your mental capabilities across several major neurological systems.

Developed For Long Term Brain Benefits

While students and high-performance professionals need instant boosts in mental clarity and drive, they are not the only ones who can benefit from nootropics.

Qualia Mind also supports those in more advanced age, when preserving the sharpness of the mind is crucial for the quality of life.

Qualia Mind supports neuron synaptic formation, acetylcholine signaling, and brain mitochondrial function, helping people optimize their memory and overall brain health.

Stimulant & Stimulant Free Option

The original Qualia Mind formula contains caffeine, which is the main working ingredient that gives you brain-boosting benefits. But containing a stimulant means you’re limited to when you can take it.

The stimulant-free option is perfect if you need a cognitive boost in the late afternoon without disrupting your sleep.

Who Is Qualia Mind For?

Those Conscious Of Brain Health

Qualia Mind was designed for short-term brain-boosting benefits and long-term brain health. Many ingredients help with cognitive function in elderly patients to reduce the effects of cognitive decline.

Taking Qualia Mind before any potential cognitive decline may keep your brain healthy longer.

Biohackers And Health Optimizers

Qualia Mind offers a sophisticated blend of ingredients designed to fine-tune brain function, promoting an edge in cognitive processes. It’s ideal for those experimenting with their physiological potential to enhance memory, focus, and overall mental clarity.

Since biohackers and health optimizers are generally in tune with their bodies, they’ll notice if Qualia Mind works.

Students

Students may find Qualia Mind beneficial for its potential to support concentration, learning, and memory recall. Taking it before long study sessions or exams can be a better option than prescription drugs that have addicting qualities.

Busy Professionals

Busy professionals can benefit from the heightened focus and mental stamina it aims to provide, helping to manage workload efficiently while maintaining high levels of creativity and problem-solving skills.

My Experience With Qualia Mind

Qualia Mind Nootropic

Qualia Mind straight-up works. And, of course, it does, as it contains caffeine and L-theanine, the most potent nootropic stack. The L-theanine takes the edge off the caffeine, and combined with other non-stimulant brain-boosting ingredients, Qualia Mind provides smooth energy.

I took Qualia Mind before writing this review (and before other mentally demanding) tasks, and I feel “locked in” after about 20-30 minutes.

I can motor through this mentally demanding task with clearer thoughts and more creativity. I haven’t tried the stimulant-free version, so I can’t say if you’ll have the same benefits.

User Reviews & Testimonials

Qualia Mind reviews are overwhelmingly positive, and I am talking about not just a handful of them but over 2000 customer reviews on their website and over 1000 on Amazon. Here are some of the superlatives:

“The last quarter of the year is stressful for my profession and I found Qualia Mind noticeably helped me focus and improved my memory. I felt like it gave me an edge I’d been missing.”- Susan L.

“The First serving improved my mood and energy. Zero crash nor any type of withdrawal. I absolutely love Qualia Mind effect on my wellbeing. I’ve spent thousands of dollars on other neutropics & supplements and this product is superior”- Tabitha M.

Despite the thousands of happy customers, some don’t feel any effect, and you can find multiple reviews of this type. So, as is the case with supplements, not everyone reacts the same to them:

“Nothing against the product, since it’s a supplement and works differently for different people. In my case, it just did not work, and I felt a bit dizzy and not great.

My problem is the return policy, if a product does not serve its purpose, it should be returned, but unfortunately, I cannot return it!”

Qualia Mind Side Effects

How Much Caffeine Is In Qualia Mind

While Qualia Mind is designed to support cognitive enhancement, potential side effects could include jitteriness, headache, stomach upset, or insomnia, primarily due to its caffeine content and potent nootropic ingredients.

I didn’t feel any adverse side effects taking Qualia Mind, but if you’re caffeine-sensitive, you might.

Consult with a healthcare provider before starting any new supplement regimen, especially for those with pre-existing conditions or those taking other medications, to ensure safety and avoid adverse reactions.

Qualia Mind Alternatives

If you’ve gotten this far and not convinced on Qualia Mind, here’s some alternatives to consider.

Nooceptin

Nooceptin Nootropic

Nooceptin is a nootropic developed by SAP Nutra that aims to increase memory, attention, and overall cognitive performance without the use of stimulants. It offers long-term brain health benefits rather than immediate results.

It offers advantages such as improved memory, focus, and a sustained boost without the crash associated with caffeine-containing products. Nooceptin is appropriate for students, gamers, professionals, and elderly people looking to improve their cognitive abilities.

The brain supplement contains ingredients such as Lion’s Mane Extract, Citicoline, Rhodiola Rosea Extract, L-Theanine, Bacopa Monnieri Extract, Ginkgo Biloba Extract, and Panax Ginseng Extract.

While some of these substances have been proven to be helpful, others are currently being studied. Nooceptin is touted as a non-stimulant option for long-term cognitive improvement, with improvements usually noticeable 7-14 days after you start taking it.

Despite its potentially underdosed components and higher cost, Nooceptin could be a valuable tool for those seeking a stimulant-free cognitive boost.

My Nooceptin review breaks this down further.

Vyvamind

Vyvamind

Vyvamind is a nootropic supplement that contains caffeine and L-theanine to improve concentration and cognitive function. Users claim increased focus, vitality, and cognitive abilities without substantial crashes.

Vyvamind’s formulation, which contains less L-tyrosine and citicoline than research recommendations, is intended to supplement the main nootropic combination of caffeine and L-theanine.

This combination is well known for improving concentration and cognitive function. The supplement is touted as a non-stimulant alternative aimed at clients who choose a more natural and less intensive approach to mental development.

Vyvamind is great for coffee-averse people, busy professionals who need a focus boost, and students during study sessions.

My Vyvamind review breaks this down further.

NooCube

NooCube

NooCube is a popular brain-boosting product due to its claimed quick cognitive effects. The ingredients in NooCube include Bacopa Monnieri, L-Tyrosine, and L-Theanine.

These are commonly known as having mental health benefits. Several substances, including Huperzine-A and Alpha GPC, are speculative without conclusive research.

NooCube is intended to improve cognition and alertness without using stimulants, and the amounts of each ingredient are explicitly listed.

NooCube is especially good for working professionals, students, the elderly, gamers, and combat athletes because it offers numerous cognitive benefits without the jittery side effects associated with caffeine.

My NooCube review breaks this down further.

Frequently Asked Qualia Mind Questions

How Long Does It Take Qualia Mind To Work?

In my experience, it takes 20-30 minutes for Qualia Mind to work. It may take shorter or longer depending on whether you take it on an empty stomach or after a large meal.

Is Qualia Mind Healthy?

Qualia Mind is healthy and only contains natural herbs and ingredients. As always, individual mileage may vary.

Can You Take Qualia Mind Every Day?

You can take Qualia Mind every day as there is no tolerance or addictive qualities. However, it’s expensive, costing $6-7 per serving.

How Does Qualia Mind Make You Feel?

Qualia Mind makes you feel “dialed in” and focused on your task. The energy is smooth, and you don’t have unwanted jitters or energy crashes like you do with coffee or energy drinks.

How Much Caffeine Is In Qualia Mind?

Qualia Mind contains 90 mg of caffeine. Similar to a cup of coffee. However, the addition of L-theanine takes the edge off caffeine, reducing anxiety and jitters.

Summary

Qualia Mind is an excellent nootropic supplement marketed toward the high-end customer. However, it works, unlike other cheap nootropics like BrainPill.

The Qualia Mind formula is similar to other brands that charge 3-4 times less per serving, so it may be worth seeking other alternatives if price is a barrier.

Qualia Mind

Qualia Mind Nootropic

A premium nootropic blend designed for short and long term brain boosting benefits.

CHECK CURRENT DEALS
Qualia Mind

References

  1. Szewczyk, A., Andres-Mach, M., Zagaja, M., Kaczmarczyk-Ziemba, A., Maj, M., & Szala-Rycaj, J. (2023). The Effect of a Diet Enriched with Jerusalem artichoke, Inulin, and Fluoxetine on Cognitive Functions, Neurogenesis, and the Composition of the Intestinal Microbiota in Mice. Current Issues in Molecular Biology, 45(3), 2561-2579.
  2. Ghahramani, M., Zare, Y., & Kohanpour, M. A. (2021). The Effect of Consuming Artichoke Extract with Aerobic Training on Blood Glucose and Insulin Resistance and Its Relationship with the Cognitive Status in Elderly with Mild Cognitive Impairment. Journal of Sport Biosciences, 13(4), 439-450.
  3. Iglesias-Carres, L., Bruno, A., D’Antuono, I., Linsalata, V., Cardinali, A., & Neilson, A. P. (2023). In vitro evidences of the globe artichoke antioxidant, cardioprotective and neuroprotective effects. Journal of Functional Foods, 107, 105674.
  4. Singh, H. K., & Dhawan, B. N. (1997). NEUROPSYCHOPHARMACOLOGICAL EFFECTS OF THE AYURVEDIC NOOTROPlC BACOPA MONNlERA LINN.(BRAHMI). Indian Journal of Pharmacology, 29(5), 359-365.
  5. Calabrese, C., Gregory, W. L., Leo, M., Kraemer, D., Bone, K., & Oken, B. (2008). Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. The journal of alternative and complementary medicine, 14(6), 707-713.
  6. Kongkeaw, C., Dilokthornsakul, P., Thanarangsarit, P., Limpeanchob, N., & Scholfield, C. N. (2014). Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. Journal of ethnopharmacology, 151(1), 528-535.
  7. Pase, M. P., Kean, J., Sarris, J., Neale, C., Scholey, A. B., & Stough, C. (2012). The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials. The Journal of Alternative and Complementary Medicine, 18(7), 647-652.
  8. Cropley, M., Banks, A. P., & Boyle, J. (2015). The effects of Rhodiola rosea L. extract on anxiety, stress, cognition and other mood symptoms. Phytotherapy research, 29(12), 1934-1939.
  9. Malík, M., & Tlustoš, P. (2022). Nootropics as cognitive enhancers: types, dosage and side effects of smart drugs. Nutrients, 14(16), 3367.
  10. Wood, D. R., Reimherr, F. W., & Wender, P. H. (1985). Treatment of attention deficit disorder with DL-phenylalanine. Psychiatry Research, 16(1), 21-26.
  11. Beckmann, H., Strauss, M. A., & Ludolph, E. (1977). Dl-phenylalanine in depressed patients: an open study. Journal of Neural Transmission, 41(2-3), 123-134.
  12. Akram, M., Daniyal, M., Ali, A., Zainab, R., Shah, S. M. A., Munir, N., & Tahir, I. M. (2020). Role of phenylalanine and its metabolites in health and neurological disorders. In Synucleins-Biochemistry and Role in Diseases. IntechOpen.
  13. Steenbergen, L., Sellaro, R., Hommel, B., & Colzato, L. S. (2015). Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia, 69, 50-55.
  14. Jongkees, B. J., Hommel, B., Kühn, S., & Colzato, L. S. (2015). Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands—A review. Journal of psychiatric research, 70, 50-57.
  15. Souza, D. B., Del Coso, J., Casonatto, J., & Polito, M. D. (2017). Acute effects of caffeine-containing energy drinks on physical performance: a systematic review and meta-analysis. European journal of nutrition, 56(1), 13-27.
  16. Waldron, M., Patterson, S. D., Tallent, J., & Jeffries, O. (2018). The effects of an oral taurine dose and supplementation period on endurance exercise performance in humans: a meta-analysis. Sports Medicine, 48, 1247-1253.
  17. Steenbergen, L., Sellaro, R., Hommel, B., & Colzato, L. S. (2015). Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia, 69, 50-55.
  18. Hidese, S., Ogawa, S., Ota, M., Ishida, I., Yasukawa, Z., Ozeki, M., & Kunugi, H. (2019). Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: a randomized controlled trial. Nutrients, 11(10), 2362.
  19. Williams, J. L., Everett, J. M., D’Cunha, N. M., Sergi, D., Georgousopoulou, E. N., Keegan, R. J., … & Naumovski, N. (2020). The effects of green tea amino acid L-theanine consumption on the ability to manage stress and anxiety levels: A systematic review. Plant foods for human nutrition, 75, 12-23.
  20. Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., & Scholey, A. B. (2008). The effects of L-theanine, caffeine and their combination on cognition and mood. Biological psychology, 77(2), 113-122.
  21. Owen, G. N., Parnell, H., De Bruin, E. A., & Rycroft, J. A. (2008). The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutritional neuroscience, 11(4), 193-198.
  22. Traini, E., Bramanti, V., & Amenta, F. (2013). Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline-containing phospholipid with a still interesting profile as cognition enhancing agent. Current Alzheimer Research, 10(10), 1070-1079.
  23. Sagaro, G. G., Traini, E., & Amenta, F. (2023). Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis. Journal of Alzheimer’s Disease, (Preprint), 1-12.
  24. Kansakar, U., Trimarco, V., Mone, P., Varzideh, F., Lombardi, A., & Santulli, G. (2023). Choline supplements: An update. Frontiers in Endocrinology, 14, 1148166.
  25. Moreno, M. D. J. M. (2003). Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial. Clinical therapeutics, 25(1), 178-193.
  26. Parker, A. G., Byars, A., Purpura, M., & Jäger, R. (2015). The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility. Journal of the International Society of Sports Nutrition, 12(sup1), P41.
  27. Astorino, T. A., & Roberson, D. W. (2010). Efficacy of acute caffeine ingestion for short-term high-intensity exercise performance: a systematic review. The Journal of Strength & Conditioning Research, 24(1), 257-265.
  28. Southward, K., Rutherfurd-Markwick, K. J., & Ali, A. (2018). The effect of acute caffeine ingestion on endurance performance: a systematic review and meta-analysis. Sports Medicine, 48(8), 1913-1928.
  29. Waller, G., Dolby, M., Steele, J., & Fisher, J. P. (2020). A low caffeine dose improves maximal strength, but not relative muscular endurance in either heavier-or lighter-loads, or perceptions of effort or discomfort at task failure in females. PeerJ, 8, e9144.
  30. Spriet, L. L. (2014). Exercise and sport performance with low doses of caffeine. Sports medicine, 44, 175-184.
  31. Adefegha, S. A., Oboh, G., Oyeleye, S. I., Dada, F. A., Ejakpovi, I., & Boligon, A. A. (2017). Cognitive enhancing and antioxidative potentials of velvet beans (Mucuna pruriens) and horseradish (Moringa oleifera) seeds extracts: a comparative study. Journal of Food Biochemistry, 41(1), e12292.
  32. Lebedev, A. V., Nilsson, J., Lindström, J., Fredborg, W., Akenine, U., Hillilä, C., … & Lövdén, M. (2020). Effects of daily L-dopa administration on learning and brain structure in older adults undergoing cognitive training: a randomised clinical trial. Scientific Reports, 10(1), 5227.
  33. Yurko-Mauro, K., Alexander, D. D., & Van Elswyk, M. E. (2015). Docosahexaenoic acid and adult memory: a systematic review and meta-analysis. PloS one, 10(3), e0120391.
  34. Kim, M. S., Bang, J. H., Lee, J., Han, J. S., Baik, T. G., & Jeon, W. K. (2016). Ginkgo biloba L. extract protects against chronic cerebral hypoperfusion by modulating neuroinflammation and the cholinergic system. Phytomedicine, 23(12), 1356-1364.
  35. Stough, C., Clarke, J., Lloyd, J., & Nathan, P. J. (2001). Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants. International Journal of Neuropsychopharmacology, 4(2), 131-134.
  36. Canter, P. H., & Ernst, E. (2007). Ginkgo biloba is not a smart drug: an updated systematic review of randomised clinical trials testing the nootropic effects of G. biloba extracts in healthy people. Human Psychopharmacology: Clinical and Experimental, 22(5), 265-278.
  37. Li, J., Wu, H. M., Zhou, R. L., Liu, G. J., & Dong, B. R. (2008). Huperzine A for Alzheimer’s disease. Cochrane Database of Systematic Reviews, (2).
  38. Mei, Z., Zheng, P., Tan, X., Wang, Y., & Situ, B. (2017). Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury. Metabolic Brain Disease32, 1861-1869.
  39. Ghassab?Abdollahi, N., Mobasseri, K., Dehghani Ahmadabad, A., Nadrian, H., & Mirghafourvand, M. (2021). The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews. Phytotherapy Research35(9), 4971-4987.
  40. Chen N, Yang M, Zhou M, Xiao J, Guo J, He L. L-carnitine for cognitive enhancement in people without cognitive impairment. Cochrane Database Syst Rev. 2017 Mar 26;3(3):CD009374. doi: 10.1002/14651858.CD009374.pub3. PMID: 28349514; PMCID: PMC6464592.
  41. Pennisi, M., Lanza, G., Cantone, M., D’Amico, E., Fisicaro, F., Puglisi, V., … & Malaguarnera, G. (2020). Acetyl-L-carnitine in dementia and other cognitive disorders: a critical update. Nutrients, 12(5), 1389.
  42. Kobayashi, S., Iwamoto, M., Kon, K., Waki, H., Ando, S., & Tanaka, Y. (2010). Acetyl?l?carnitine improves aged brain function. Geriatrics & gerontology international, 10, S99-S106.
  43. Montgomery, S. A., Thal, L. J., & Amrein, R. (2003). Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer’s disease. International clinical psychopharmacology, 18(2), 61-71.
  44. Pooyandjoo, M., Nouhi, M., Shab?Bidar, S., Djafarian, K., & Olyaeemanesh, A. (2016). The effect of (L?) carnitine on weight loss in adults: a systematic review and meta?analysis of randomized controlled trials. Obesity reviews, 17(10), 970-976.
  45. Veronese, N., Stubbs, B., Solmi, M., Ajnakina, O., Carvalho, A. F., & Maggi, S. (2018). Acetyl-L-carnitine supplementation and the treatment of depressive symptoms: a systematic review and meta-analysis. Psychosomatic medicine, 80(2), 154-159.
  46. Nakazaki, E., Mah, E., Sanoshy, K., Citrolo, D., & Watanabe, F. (2021). Citicoline and memory function in healthy older adults: a randomized, double-blind, placebo-controlled clinical trial. The Journal of Nutrition, 151(8), 2153-2160.
  47. Jasielski, P., Pi?del, F., Piwek, M., Rocka, A., Petit, V., & Rejdak, K. (2020). Application of citicoline in neurological disorders: a systematic review. Nutrients, 12(10), 3113.
  48. Kamohara, S. (2016). An evidence-based review: Anti-obesity effects of Coleus forskohlii. Personalized Medicine Universe, 5, 16-20.
  49. Godard, M. P., Johnson, B. A., & Richmond, S. R. (2005). Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obesity research, 13(8), 1335-1343.
  50. Henderson, S., Magu, B., Rasmussen, C., Lancaster, S., Kerksick, C., Smith, P., … & Kreider, R. B. (2005). Effects of coleus forskohlii supplementation on body composition and hematological profiles in mildly overweight women. Journal of the International Society of Sports Nutrition, 2(2), 1-9.

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James de Lacey James is a professional strength & conditioning coach that works with professional and international level teams and athletes. He owns Sweet Science of Fighting, is a published scientific researcher and has completed his Masters in Sport & Exercise Science. He's combined my knowledge of research and experience to bring you the most practical bites to be applied to your combat training.